In Depth: Chronic wounds

Biofilms

Virtually all wounds contain bacteria but the type and number of bacteria, their phenotype, as well as the way they are organized determine to what extent they may be harmful to a (skin) lesion and its healing process.
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Debridement

The presence of a biofilm in a wound is known to be detrimental to wound healing as is the case with the presence of necrosis or slough. Thus, the removal of these harmful aspects, debridement, is essential for creating a healing wound environment.
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